On the upside, loss of the Y chromosome also appeared to make bladder cancer more susceptible to immunotherapy drugs called immune checkpoint inhibitors, the researchers reported June 21 in Nature. The new study, carried out in both mice and humans, found that loss of the Y chromosome in bladder cancer cells helped tumors evade the immune system and grow unchecked. More than half of males in their early 90s have lost the Y chromosome in some of their blood cells. But as males grow older, some of their cells may naturally lose the Y chromosome. Most biological females have two X chromosomes in every cell, whereas most biological males have one X and one Y chromosome. The most recent evidence comes from a new study that suggests that the Y chromosome may actually protect men from aggressive bladder cancer. But over the past few years, results from multiple studies have challenged that belief. It was once thought that after guiding the development of male sex organs in a fetus, the Y chromosome didn’t do much else. Credit: National Human Genome Research Institute
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |